Descripción
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Background & aims Inflammationmarkers (IM) have been associated with the development of chronic diseases. This study compares the effects on IM of three exercise programs combined with ahypocaloricdiet. Methods 119 overweight participants (73 women, 46 men) aged 18?50 years were randomised into four treatment groups: strength training (S; n = 30), endurance training (E; n = 30), combined S + E (SE; n = 30), and adiet and physical activity recommendations group (D; n = 29). Energy intake, anthropometric variables (AV), training variables (VO2peak, strength index, dynamometric strength index [DSI]) and plasma IM were recorded at baseline and after 22 weeks of treatment. Results 84 participants completed the study. At 22 weeks, all groups showed a significantly reduced energy intake (P < 0.001) and improved AV (P < 0.001). VO2peak significantly increased in all groups (P < 0.01). DSI increased in the exercise groups only (P < 0.05). Plasma leptin fell significantly (P < 0.001) in the S and E groups, but not significantly in the SE group (P = 0.029) (no significant differences between these groups). Tumour necrosis factor-? (TNF-?), and C-reactive protein (CRP) concentrations decreased in all groups when examined together, but not when examined separately. No significant differences were seen in interleukin-6 (IL-6). Conclusions Combining strength or endurance training with ahypocaloricdiet improved AV and reduced plasma leptin concentrations. No differences were seen between groups in terms of TNF-?, IL-6 or CRP reduction. | |
Internacional
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Si |
JCR del ISI
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Si |
Título de la revista
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Clinical Nutrition |
ISSN
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0261-5614 |
Factor de impacto JCR
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3,41 |
Información de impacto
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Datos JCR del año 2010 |
Volumen
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DOI
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http://dx.doi.org/10.1016/j.clnu.2012.10.015 |
Número de revista
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Desde la página
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13 |
Hasta la página
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17 |
Mes
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SIN MES |
Ranking
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