Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Characterizing And Extracting the Synaptic Apposition Surface For the Analysis of Synaptic Geometry
Year:2011
Research Areas
  • Computer applications
Information
Abstract
Studying the geometry of synaptic junctions enables new hy- potheses to be established regarding chemical communication between neurons. Morphological studies of these structures is greatly facilitated by the use of recent electron microscopy techniques that permit 3D re- construction of large numbers of synapses. Two critical components of the synaptic junction are the active zone and the postsynaptic density, as they are directly related to the synaptic release probability and the num- ber of postsynaptic receptors, respectively. Given that these two struc- tures are in close apposition, they can be represented by a single surface, the synaptic apposition surface. We have developed a technique to auto- matically extract this surface and the features of this structure that are most relevant to researchers interested in studying synaptic function.
International
Si
Congress
5th Workshop on Data Mining in Functional Genomics and Proteomics: current trends and future directions
960
Place
Atenas, Grecia
Reviewers
Si
ISBN/ISSN
Start Date
05/09/2011
End Date
05/09/2011
From page
63
To page
72
Proc. of the 5th Workshop on Data Mining in Functional Genomics and Proteomics: current trends and future directions
Participants
  • Autor: Juan Morales Del Olmo (UPM)
  • Autor: Angel Rodriguez Mtnez.de Bartolome (UPM)
  • Autor: José Rodrigo-Rodríguez (CSIC)
  • Autor: Javier De Felipe Oroquieta (UPM)
  • Autor: Angel Merchan Perez (UPM)
Research Group, Departaments and Institutes related
  • Creador: Departamento: Arquitectura y Tecnología de Sistemas Informáticos
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)