Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Central pain augmentation in fibromyalgia during subjectively-matched mechanical stimulation
Year:2012
Research Areas
  • Natural sciences and health sciences,
  • Electronic technology and of the communications
Information
Abstract
Fibromyalgia is a syndrome characterized by chronic widespread pain and reduced pain thresholds during somatosensory stimulation. The existence of central pain augmentation in this condition is evidenced by the fact that, when subjected to the same amount of stimulation, patients show enhanced brain responses as compared to controls. In the present work, magnetoencephalography was used to obtain brain responses to mechanical pressure both above and below the pain threshold. Activity was recorded from 9 patients and 9 control subjects using a purpose-built stimulator. The amount of pressure was adjusted to produce similar subjective levels of pain in both groups. The comparison of differences between brain responses evoked by stimulation above and below the pain threshold revealed increases in amplitude in somatosensory, temporal, parietal and prefrontal areas at short latencies and in prefrontal areas at long latencies in favour of patients as compared to control subjects. Therefore, in addition to showing increased responses when the objective level of stimulation is kept the same as for control subjects, fibromyalgia patients show central pain augmentation after adjusting the amount of pressure to produce similar subjective levels of pain in both groups.
International
Si
Congress
8th FENS Forum of Neuroscience
960
Place
BARCELONA
Reviewers
Si
ISBN/ISSN
Start Date
14/07/2012
End Date
18/07/2012
From page
1
To page
1
Participants
  • Autor: Francisco del Pozo Guerrero (UPM)
  • Autor: Ceferino Maestu Unturbe (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Grupo de Bioingeniería y Telemedicina
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