Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Dissecting Arabidopsis Gbeta signal transduction on the protein surface.
Year:2012
Research Areas
  • Molecular biology
Information
Abstract
The heterotrimeric G-protein complex provides signal amplification and target specificity. The Arabidopsis (Arabidopsis thaliana) G?-subunit of this complex (AGB1) interacts with and modulates the activity of target cytoplasmic proteins. This specificity resides in the structure of the interface between AGB1 and its targets. Important surface residues of AGB1, which were deduced from a comparative evolutionary approach, were mutated to dissect AGB1-dependent physiological functions. Analysis of the capacity of these mutants to complement well-established phenotypes of G?-null mutants revealed AGB1 residues critical for specific AGB1-mediated biological processes, including growth architecture, pathogen resistance, stomata-mediated leaf-air gas exchange, and possibly photosynthesis. These findings provide promising new avenues to direct the finely tuned engineering of crop yield and traits.
International
Si
JCR
Si
Title
Plant Physiology
ISBN
0032-0889
Impact factor JCR
6,535
Impact info
Volume
159
10.1104/pp.112.196337
Journal number
From page
975
To page
983
Month
JULIO
Ranking
Revista en el primer cuartil de su categoría (7ª de 190).
Participants
  • Autor: Antonio Molina Fernandez (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Interacciones Moleculares Planta-Patógeno
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
  • Departamento: Biotecnología
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)