Observatorio de I+D+i UPM

Memorias de investigación
Microscopy image analysis for the study of embryo development
Research Areas
  • Natural sciences and health sciences,
  • Biomedicine,
  • Engineering,
  • Electronic technology and of the communications
The understanding of the processes underlying embryo development from a single cell into a multicellular organism is a longterm goal of Development Biology that is recently being feasible thanks to the availability of massive 3D+t complex data acquired with new microscopy technologies. But these large quantities of data require automated or semi-automated image processing methods to be possible. Current developments and challenges in biological image processing include algorithms for microscopy multiview fusion, cell nucleus tracking for lineage reconstruction, cell segmentation, multidimensional image registration and gene expression atlases. These tools are to eventually produce in toto reconstruction of the embryo development combining the cell lineage tree with quantitative gene expression data in its spatio-temporal context. ln this work several processing tools developed by our group will be presented: like a multiview image fusion for Light-Sheet Fluorescence Microscopy , a cell lineage reconstruction workflow for early stages of embryo development ] and on-going work on the construction of gene expression atlases of embryogenesis.
Universitat de Barcelona
Entity Nationality
Barcelona, España
  • Autor: Andres de Santos Lleo (UPM)
  • Autor: Miguel Angel Luengo Oroz (UPM)
  • Autor: Carlos Castro Gonzalez (UPM)
  • Autor: David Pastor Escuredo (UPM)
  • Autor: Maria Jesus Ledesma Carbayo (UPM)
Research Group, Departaments and Institutes related
  • Creador: Departamento: Ingeniería Electrónica
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)