Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Semantic Interoperability Solution for Multicentric Breast Cancer Trials at the INTEGRATE EU Project
Year:2013
Research Areas
  • Biomedicine,
  • Information technology and adata processing
Information
Abstract
The introduction of ?omic information within current clinical treatment is one of the main challenges to transfer the huge amount of genomic-based results. The number of potential translational clinical trials is therefore experiencing a dramatic increase, with the corresponding increment on patient variability. Such scenario requires a larger population to recruit a minimum set of patients that may involve multi-centric trials, with associated challenges on heterogeneous data integration. To ensure sustainability on clinical trial management, semantic interoperability is one of the main goals addressed by international initiatives such as the EU funded INTEGRATE project: ?Driving Excellence in Integrative Cancer Research?. This paper describes the approach adopted within an international research initiative, providing a homogeneous platform to manage clinical information from patients on breast cancer clinical trials. Following the project ?leitmotif? of reusing standards supported by a large community, we have developed a solution providing a common data model (i.e. HL7 RIM-based), a biomedical domain vocabulary (i.e. SNOMED) as core dataset and resources from the semantic web community adapted for the biomedical domain. After one year and a half of collaboration, the INTEGRATE consortium has been able to develop a solution providing the reasoning capabilities required to solve clinical trial patient recruitment. The next challenge will be to extend the current solution to support a cohort selection tool allowing prospective analysis and predictive modeling.
International
Si
Congress
Healthinf 2013, VI International Confenrence on Health Informatics
960
Place
Barcelona
Reviewers
Si
ISBN/ISSN
978-989-8565-37-2
Start Date
11/02/2013
End Date
14/02/2013
From page
34
To page
41
HEALTHINF 2013 - Proceedings of the International Conference on Health Informatics, Barcelona, Spain, 11-14 February, 2013.
Participants
  • Autor: Sergio Paraiso-Medina (UPM)
  • Autor: David Perez Del Rey (UPM)
  • Autor: Raul Alonso Calvo (UPM)
  • Autor: Bretch Claerhout (Custodix Ltd.)
  • Autor: Kristof de Schepper
  • Autor: P Hennebert
  • Autor: J LHaut
  • Autor: J Van Leuween
  • Autor: Anca Bucur (Philips Research)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Grupo de Informática Biomédica (GIB)
  • Departamento: Inteligencia Artificial
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