Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Bayesian network modeling of the consensus between experts: An application to neuron classification
Year:2013
Research Areas
  • Artificial intelligence,
  • Neurophysiology,
  • Biology
Information
Abstract
Neuronal morphology is hugely variable across brain regions and species, and their classification strategies are a matter of intense debate in neuroscience. GABAergic cortical interneurons have been a challenge because it is difficult to find a set of morphological properties which clearly define neuronal types. A group of 48 neuroscience experts around the world were asked to classify a set of 320 cortical GABAergic interneurons according to the main features of their three-dimensional morphological reconstructions. A methodology for building a model which captures the opinions of all the experts was proposed. First, one Bayesian network was learned for each expert, and we proposed an algorithm for clustering Bayesian networks corresponding to experts with similar behaviors. Then, a Bayesian network which represents the opinions of each group of experts was induced. Finally, a consensus Bayesian multinet which models the opinions of the whole group of experts was built. A thorough analysis of the consensus model identified different behaviors between the experts when classifying the interneurons in the experiment. A set of characterizing morphological traits for the neuronal types was defined by performing inference in the Bayesian multinet. These findings were used to validate the model and to gain some insights into neuron morphology.
International
Si
JCR
Si
Title
International Journal of Approximate Reasoning
ISBN
0888-613X
Impact factor JCR
1,948
Impact info
Datos JCR del año 2011
Volume
http://dx.doi.org/10.1016/j.ijar.2013.03.011
Journal number
From page
in
To page
press
Month
SIN MES
Ranking
Participants
  • Autor: Pedro Luis Lopez Cruz (UPM)
  • Autor: Pedro Maria Larrañaga Mugica (UPM)
  • Autor: Javier De Felipe Oroquieta (UPM)
  • Autor: Maria Concepcion Bielza Lozoya (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: COMPUTATIONAL INTELLIGENCE GROUP
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Inteligencia Artificial
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)