Descripción
|
|
---|---|
The impact of the Parkinson's disease and its treatment on the patients' health-related quality of life can be estimated either by means of generic measures such as the european quality of Life-5 Dimensions (EQ-5D) or specific measures such as the 8-item Parkinson's disease questionnaire (PDQ-8). In clinical studies, PDQ-8 could be used in detriment of EQ-5D due to the lack of resources, time or clinical interest in generic measures. Nevertheless, PDQ-8 cannot be applied in cost-effectiveness analyses which require generic measures and quantitative utility scores, such as EQ-5D. To deal with this problem, a commonly used solution is the prediction of EQ-5D from PDQ-8. In this paper, we propose a new probabilistic method to predict EQ-5D from PDQ-8 using multi-dimensional Bayesian network classifiers. Our approach is evaluated using five-fold cross-validation experiments carried out on a Parkinson's data set containing 488 patients, and is compared with two additional Bayesian network-based approaches, two commonly used mapping methods namely, ordinary least squares and censored least absolute deviations, and a deterministic model. Experimental results are promising in terms of predictive performance as well as the identification of dependence relationships among EQ-5D and PDQ-8 items that the mapping approaches are unable to detect | |
Internacional
|
Si |
JCR del ISI
|
Si |
Título de la revista
|
Biomedical Engineering: Applications, Basis And Communications |
ISSN
|
1016-2372 |
Factor de impacto JCR
|
0,233 |
Información de impacto
|
|
Volumen
|
26 |
DOI
|
10.4015/S101623721450015X |
Número de revista
|
1 |
Desde la página
|
1 |
Hasta la página
|
11 |
Mes
|
SIN MES |
Ranking
|