Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
Physical strength and vitamin B12 in relation to cognitive score in Spanish institutionalized elderly
Año:2007
Áreas de investigación
  • Nutrición
Datos
Descripción
Nº de revista: SUPLEMENTO 1. In the elderly there is a high prevalence of dementia often accompanied by reduced physical activity and low vitamin B12 levels. Various animal and human studies provide evidence for the potential of physical exercise in promoting cognitive health in later life. Aim: Assessment of the relation between physical strength, vitamin B12 status and mental health in Spanish institutionalized elderly. Methods: In 78 institutionalized elderly from Madrid (56 women, mean age 83 ±6 years) vitamin B12 status was assessed by serum cobalamin (SCbl) and Holo-Transcobalamin (HTC) status. Physical fitness was tested by hand grip and arm strength, chair stands, and standing balance, cognitive function with the Mini Mental State Examination (MMSE). For statistics, Spearman¿s rank correlation coefficient, and Kruskal-Wallis-H test were used, significance was set at p<0.05. Results: Nineteen (24.4%) were cognitively healthy (MMSE score?24), 16 (20.5%) showed a light (MMSE score 21¿23), 27 (34.6%) a moderate (MMSE score 11¿20) and 13 (16.7%) a severe dementia (MMSE score?10). MMSE scores were positively correlated with right and left hand grip, chair stands and arm strength (all p<0.05). Between the MMSE groups, there were significant differences for right hand grip, left hand grip and arm strength (p<0.05). SCbl values in the ¿no dementia¿ group were higher (521±469 pmol/l) than in the ¿severe dementia¿ group (388±202 pmol/l), but without statistical significance. The same trend was observed with HTC (59.3±50.8 vs 41.2±21.7 pmol/l). Conclusion: Physical strength is associated with cognitive function. The observed differences between vitamin B12 levels in the four cognitive function groups however were without statistical significance.
Internacional
Si
JCR del ISI
Si
Título de la revista
ANN NUTR METAB
ISSN
0250-6807
Factor de impacto JCR
1,831
Información de impacto
Volumen
51
DOI
Número de revista
1
Desde la página
119
Hasta la página
120
Mes
JUNIO
Ranking
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Participantes
  • Autor: J. CABALLERO (Centro Geriátrico Los Peñascales)
  • Autor: M.J. CASTILLO (Universidad de Granada)
  • Autor: MARÍA ÁLVAREZ SÁNCHEZ (Universidad Politécnica de Madrid)
  • Autor: MARCELA GONZÁLEZ GROSS (Universidad Politécnica de Madrid)
  • Autor: Ana Belen Peinado Lozano (UPM)
  • Autor: Agustin Melendez Ortega (UPM)
  • Autor: K. PIETRZIK (Universität Bonn)
  • Autor: R. SOLA (Universidad de Granada)
  • Autor: Victor Diaz Molina (UPM)
  • Autor: ULRIKE ALBERS (Universidad Politécnica de Madrid)
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  • Creador: Grupo de Investigación: Grupo de Inv. del Laboratorio de Fisiología del Esfuerzo
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