Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Uncertainty in optical bio-sensors due to the spectral displacement of the interference modes of the transduction signal
Year:2014
Research Areas
  • Sensors,
  • Biosensors,
  • Optician,
  • Engineering
Information
Abstract
The analysis of the interference modes has an increasing application, especially in the field of optical biosensors. In this type of sensors, the displacement of the interference modes of the transduction signal is observed when a particular biological agent is placed over the biosensor. In order to measure this displacement, the position of a maximum (or a minimum) of the signal must be detected before and after placing the agent over the sensor. A parameter of great importance for this kind of sensors is the period of the signal, which is inversely proportional to the optical thickness h0 of the sensor in the absence of the biological agent. The increase of this period improves the sensitivity of the sensor but it worsens the detection of the maximum. In this paper, authors analyze the propagation of uncertainties in these sensors when using least squares techniques for the detection of the maxima (or minima) of the signal. Techniques described in supplement 2 of the ISO GUM Guide are used. The result of the analysis allows a metrological educated answer to the question of which is the optimal period of the signal.
International
No
JCR
No
Title
Óptica pura y aplicada
ISBN
2171-8814
Impact factor JCR
Impact info
Volume
47
DOI: http://dx.doi.org/10.7149/OPA.47.1.27
Journal number
1
From page
27
To page
34
Month
ENERO
Ranking
Participants
  • Autor: Jesus de Vicente Y Oliva (UPM)
  • Autor: Miguel Holgado Bolaños (UPM)
  • Autor: Alvaro Lavin Hueros (UPM)
  • Autor: Francisco Javier Sanza Gutierrez (UPM)
  • Autor: Rafael Casquel Del Campo (UPM)
  • Autor: Maria Fe Laguna Heras (UPM)
Research Group, Departaments and Institutes related
  • Creador: Departamento: Física Aplicada e Ingeniería de Materiales
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