Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
The relationship between host lifespan and pathogen reservoir potential: An analysis in the system Arabidopsis thaliana-Cucumber mosaic virus
Year:2014
Research Areas
  • Viral pathogens of plants,
  • Plant disease
Information
Abstract
Understanding pathogen emergence is a major goal of pathology, because of the high impact of emerging diseases. Pathogens emerge onto a new host from a reservoir, hence the relevance of identifying the determinants of host's reservoir potential. Host lifespan is considered as one such determinant: short-lived hosts will invest less in defenses, being more susceptible to infection, more competent as infection sources and/or will sustain larger vector populations, and thus, are effective reservoirs for long-lived host infection. Evidence for this hypothesis derives from analyses of different hosts of multihost pathogens, and here we examine whether it holds at the within-species level by comparing two genotypes of the plant Arabidopsis thaliana that differ in life-span and in tolerance to its natural pathogen Cucumber mosaic virus. Experiments showed that defenses to the virus and its aphid vector were less efficient in the short-lived genotype that, according to model simulations, was an effective reservoir under a large range of conditions. Reservoir potential, though, was modulated by the demography of host and vector and by the genetic composition of the host population. Thus, within-species genetic diversity for lifespan and pathogen defense will result in differences in reservoir potential, which will condition infection dynamics and host-pathogen co-evolution
International
Si
JCR
Si
Title
Plos Pathogens
ISBN
1553-7374
Impact factor JCR
8,057
Impact info
Volume
10
Journal number
From page
e1004492
To page
e1004492
Month
SIN MES
Ranking
Participants
  • Autor: Jean Michel Hily (UPM)
  • Autor: Adrian Jose Garcia Puertas (UPM)
  • Autor: Arancha Moreno (ICA-CSIC)
  • Autor: Maria Plaza (ICA-CSIC)
  • Autor: Mark Denis Wilkinson (UPM)
  • Autor: Alberto Fareres (ICA-CSIC)
  • Autor: Aurora Fraile Perez (UPM)
  • Autor: Fernando Garcia-Arenal Rodriguez (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Patología Vegetal
  • Departamento: Biotecnología - Biología Vegetal
S2i 2019 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)