Artículos en revistas:
Effects of Alprazolam on Cortical Activity and Tremors in Patients with Essential Tremor
Año:2014
Áreas de investigación
- Ingenierías
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Descripción
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| Essential tremor (ET) is characterised by postural and action tremors with a frequency of 4-12 Hz. Previous studies suggest that the tremor activity originates in the cerebello-thalamocortical pathways. Alprazolam is a short-acting benzodiazepine that attenuates tremors in ET. The mechanisms that mediate the therapeutic action of alprazolam are unknown; however, in healthy subjects, benzodiazepines increase cortical beta activity. In this study, we investigated the effect of alprazolam both on beta and tremor-related cortical activity and on alterations in tremor presentation in ET patients. Therefore, we characterised the dynamics of tremor and cortical activity in ET patients after alprazolam intake. | |
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Internacional
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JCR del ISI
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Si |
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Título de la revista
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Plos One |
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ISSN
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1932-6203 |
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Factor de impacto JCR
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3,534 |
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Información de impacto
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DOI
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Desde la página
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1 |
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11 |
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Participantes
- Autor: Eduardo Rocón De Lima UPM
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
- Creador: Centro o Instituto I+D+i: Centro de Automática y Robótica (CAR). Centro Mixto UPM-CSIC