Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Mathematical modeling of neuronal connexin-36 channels
Year:2015
Research Areas
  • Natural sciences and health sciences
Information
Abstract
Neurotransmission through electrical synapses play an important role in the spike synchrony among neurons and oscillation of neuron networks. Connexin36 (Cx36) is the principal gap junction protein of electrical synapses between inhibitory interneurons in vertebrates. Coupling strength between coupled neurons is modulated, among other factor, by the voltage difference between cell interiors, termed transjunctional voltage (Vj), in a complex manner; with the Vj gradient junctional conductance of Cx36 channels first increases instantaneously (+ 20% for + 100 mV) and then it decreases slowly to half for a similar range of Vj. The significance of this regulation by voltage, a stimulus always presents and changing, in the firing properties of coupled neurons is unknown.
International
Si
Congress
FUNDACION BBVA- workshop recent advances in bioinformatics and neuroscience
970
Place
MADRID, SPAIN
Reviewers
Si
ISBN/ISSN
CDP08UPM
Start Date
09/06/2015
End Date
09/06/2015
From page
28
To page
28
Abstract_book BBVA
Participants
  • Autor: Daniel Gonzalez Nieto (UPM)
  • Autor: Luis C. Barrio
  • Autor: Ricardo Martinez-Murillo
  • Autor: Alexander Pisarchik (UPM)
  • Autor: R Jaimes-Reátegu
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Tecnologías para Ciencias de la Salud
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Tecnología Fotónica y Bioingeniería
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)