Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Assessment of a Heuristic Model for Characterization of Magnetic Nanoparticles as Contrast Agent in MRI
Year:2015
Research Areas
  • Electronic technology and of the communications
Information
Abstract
In Magnetic Resonance Imaging (MRI), the use of Magnetic Nanoparticles (MNPs) as a Contrast Agent (CA) greatly enhances the chances of identifying several diseases that are very difficult to diagnose by other means. The efficacy of a new CA is described by the longitudinal and transverse relaxivity. Nuclear Magnetic Relaxation Dispersion (NMRD) profiles represent the evolution of relaxivities with the magnetic field. Many efforts have been made to develop theoretical models to depict water proton relaxation in the presence of magnetic compounds. Theoretical models used jointly with NMRD profiles have become powerful tools to characterize MNPs as a CA. In this work, a heuristic theoretical model was implemented, verified, and assessed with different magnetic materials. It is demonstrated that the model works well when using iron cores, but fails with other magnetic compounds. A weighting factor associated to Langevin function was also introduced to the model. This extra calibration enables the model to be used with other magnetic compounds to characterize new CAs in MRI.
International
Si
JCR
No
Title
Nanobiomedicine
ISBN
1849-5435
Impact factor JCR
Impact info
Volume
10.5772/62149
Journal number
From page
1
To page
7
Month
SIN MES
Ranking
Participants
  • Autor: Jose Javier Serrano Olmedo (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Tecnologías de Apoyo a la Vida
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Tecnología Fotónica y Bioingeniería
S2i 2019 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)