Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Sensitive detection of major food allergens in breast milk: first gateway for allergenic contact during breastfeeding
Year:2015
Research Areas
  • Natural sciences and health sciences,
  • Molecular, cellular and genetic biology,
  • Plants and animal biology and ecology,
  • Biological sciences,
  • Environmental science
Information
Abstract
Food allergy is recognized as a major public health issue, especially in early childhood. It has been hypothesized that early sensitization to food allergens maybe due to their ingestion as components dissolved in the milk during the breastfeeding, explaining reaction to a food, which has never been taken before. Thus, the aim of this work has been to detect the presence of the food allergens in breast milk by microarray technology. We produced a homemade microarray with antibodies produced against major food allergens. The antibody microarray was incubated with breast milk from 14 women collected from Fundación Jiménez Díaz Hospital. In this way, we demonstrated the presence of major foods allergens in breast milk. The analysis of allergens presented in breast milk could be a useful tool in allergy prevention and could provide us a key data on the role of this feeding in tolerance induction or sensitization in children.
International
Si
JCR
Si
Title
Allergy
ISBN
0105-4538
Impact factor JCR
6,028
Impact info
Volume
70
Journal number
From page
1024
To page
1027
Month
SIN MES
Ranking
Participants
  • Autor: C Pastor-Vargas (Department of Immunology, IIS-Fundación Jimenez Diaz, Madrid, Spain.)
  • Autor: AS Maroto (Department of Immunology, IIS-Fundación Jimenez Diaz, Madrid, Spain.)
  • Autor: Araceli Diaz Perales (UPM)
  • Autor: M Villalba (Department of Biochemistry and Molecular Biology I, Universidad Complutense de Madrid, Madrid, Spain.)
  • Autor: N Casillas Díaz (Department of Pediatric, Fundación Jimenez Diaz, Madrid, Spain.)
  • Autor: F Vivanco (Department of Immunology, IIS-Fundación Jimenez Diaz, Madrid, Spain.)
  • Autor: J Cuesta-Herranz (Department of Allergy, Fundación Jimenez Diaz, Madrid, Spain.)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Biotecnología Vegetal
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
  • Departamento: Biotecnología - Biología Vegetal
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)