Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Assessment of a Heuristic Model for Characterization of Magnetic Nanoparticles as Contrast Agent in MRI
Year:2016
Research Areas
  • Electronic technology and of the communications
Information
Abstract
In Magnetic Resonance Imaging (MRI), the use of Magnetic Nanoparticles (MNPs) as a Contrast Agent (CA) greatly enhances the chances of identifying several diseases that are very difficult to diagnose by other means. The efficacy of a new CA is described by the longitudinal and transverse relaxivity. Nuclear Magnetic Relaxation Dispersion (NMRD) profiles represent the evolution of relaxivities with the magnetic field. Many efforts have been made to develop theoretical models to depict water proton relaxation in the presence of magnetic compounds. Theoretical models used jointly with NMRD profiles have become powerful tools to characterize MNPs as a CA. In this work, a heuristic theoretical model was implemented, verified, and assessed with different magnetic materials. It is demonstrated that the model works well when using iron cores, but fails with other magnetic compounds. A weighting factor associated to Langevin function was also introduced to the model. This extra calibration enables the model to be used with other magnetic compounds to characterize new CAs in MRI.
International
Si
JCR
Si
Title
Concepts in Magnetic Resonance Part a
ISBN
1546-6086
Impact factor JCR
1
Impact info
Datos JCR del año 2013
Volume
44A
10.1002/cmr.a.21361
Journal number
5
From page
279
To page
286
Month
SIN MES
Ranking
Participants
  • Autor: Nazario Félix González (UPM)
  • Autor: Marco Cesar Maicas Ramos (UPM)
  • Autor: Ana Lorena Urbano Bojorge (UPM)
  • Autor: Francisco del Pozo Guerrero (UPM)
  • Autor: Jose Javier Serrano Olmedo (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Tecnologías para Ciencias de la Salud
  • Departamento: Tecnología Fotónica y Bioingeniería
  • Grupo de Investigación: Tecnologías de Apoyo a la Vida
S2i 2019 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)