Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
Assessment of a Heuristic Model for Characterization of Magnetic Nanoparticles as Contrast Agent in MRI
Año:2016
Áreas de investigación
  • Tecnología electrónica y de las comunicaciones
Datos
Descripción
In Magnetic Resonance Imaging (MRI), the use of Magnetic Nanoparticles (MNPs) as a Contrast Agent (CA) greatly enhances the chances of identifying several diseases that are very difficult to diagnose by other means. The efficacy of a new CA is described by the longitudinal and transverse relaxivity. Nuclear Magnetic Relaxation Dispersion (NMRD) profiles represent the evolution of relaxivities with the magnetic field. Many efforts have been made to develop theoretical models to depict water proton relaxation in the presence of magnetic compounds. Theoretical models used jointly with NMRD profiles have become powerful tools to characterize MNPs as a CA. In this work, a heuristic theoretical model was implemented, verified, and assessed with different magnetic materials. It is demonstrated that the model works well when using iron cores, but fails with other magnetic compounds. A weighting factor associated to Langevin function was also introduced to the model. This extra calibration enables the model to be used with other magnetic compounds to characterize new CAs in MRI.
Internacional
Si
JCR del ISI
Si
Título de la revista
Concepts in Magnetic Resonance Part a
ISSN
1546-6086
Factor de impacto JCR
1
Información de impacto
Datos JCR del año 2013
Volumen
44A
DOI
10.1002/cmr.a.21361
Número de revista
5
Desde la página
279
Hasta la página
286
Mes
SIN MES
Ranking
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Nazario Félix González (UPM)
  • Autor: Marco Cesar Maicas Ramos (UPM)
  • Autor: Ana Lorena Urbano Bojorge (UPM)
  • Autor: Francisco del Pozo Guerrero (UPM)
  • Autor: Jose Javier Serrano Olmedo (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Tecnologías para Ciencias de la Salud
  • Departamento: Tecnología Fotónica y Bioingeniería
  • Grupo de Investigación: Tecnologías de Apoyo a la Vida
S2i 2018 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)