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Descripción
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| We study a general reaction-diffusion model for acid-mediated tumor invasion, where tumor cells produce excess acid that primarily kills healthy cells, and thereby invade the microenvironment. Under appropriate assumptions on model parameters and on initial data, it is shown that the unique heterogeneous state is nonlinearly stable, which implies a long-term coexistence of the healthy and tumor cells in certain parameter space. Our theoretical result suggests that acidity may play a significant role in heterogeneous tumor progression. | |
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Internacional
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JCR del ISI
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Título de la revista
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Mathematical Biosciences and Engineering |
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ISSN
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1547-1063 |
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Factor de impacto JCR
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Información de impacto
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Volumen
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13 |
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DOI
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10.3934/mbe.2016.13.193. |
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Número de revista
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1 |
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Desde la página
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193 |
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Hasta la página
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207 |
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Mes
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FEBRERO |
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Ranking
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