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Descripción
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| In spite of being structurally highly homologous, the two isoforms Bet v 1a (Bet v 1.0101) and Bet v 1d (Bet v 1.0102) of the major birch pollen allergen have diverse allergenic potency: Bet v 1a is allergenic, but Bet v 1d is regarded a hypoallergen. We hypothesized that the ligand-binding capacity of these lipocalin-like molecules could discriminate the level of allergenicity. We investigated thus whether the active vitamin A metabolite retinoic acid (RA) can bind to Bet v 1a or Bet v 1d, and how this affects their allergenicity in vitro . | |
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Internacional
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Si |
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Nombre congreso
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EAACI 2016 |
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Tipo de participación
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970 |
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Lugar del congreso
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Viena |
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Revisores
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Si |
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ISBN o ISSN
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1398-9995 |
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DOI
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Fecha inicio congreso
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11/06/2016 |
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Fecha fin congreso
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15/06/2016 |
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Desde la página
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505 |
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Hasta la página
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506 |
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Título de las actas
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Late Breaking Poster Session LB TPS 6. New treatment modalities in Immunotherapy |