Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Test-retest reliability of resting-state magnetoencephalography power in sensor and source space
Year:2016
Research Areas
  • Electronic technology and of the communications
Information
Abstract
Several studies have reported changes in spontaneous brain rhythms that could be used as clinical biomarkers or in the evaluation of neuropsychological and drug treatments in longitudinal studies using magnetoencephalography (MEG). There is an increasing necessity to use these measures in early diagnosis and pathology progression; however, there is a lack of studies addressing how reliable they are. Here, we provide the first test-retest reliability estimate of MEG power in resting-state at sensor and source space. In this study, we recorded 3 sessions of resting-state MEG activity from 24 healthy subjects with an interval of a week between each session. Power values were estimated at sensor and source space with beamforming for classical frequency bands: delta (2?4 Hz), theta (4?8 Hz), alpha (8?13 Hz), low beta (13?20 Hz), high beta (20?30 Hz), and gamma (30?45 Hz). Then, test-retest reliability was evaluated using the intraclass correlation coefficient (ICC). We also evaluated the relation between source power and the within-subject variability. In general, ICC of theta, alpha, and low beta power was fairly high (ICC?>?0.6) while in delta and gamma power was lower. In source space, fronto-posterior alpha, frontal beta, and medial temporal theta showed the most reliable profiles. Signal-to-noise ratio could be partially responsible for reliability as low signal intensity resulted in high within-subject variability, but also the inherent nature of some brain rhythms in resting-state might be driving these reliability patterns. In conclusion, our results described the reliability of MEG power estimates in each frequency band, which could be considered in disease characterization or clinical trials
International
Si
JCR
Si
Title
Human Brain Mapping
ISBN
1065-9471
Impact factor JCR
4,962
Impact info
Volume
37
10.1002/hbm.23027
Journal number
1
From page
179
To page
190
Month
OCTUBRE
Ranking
Participants
  • Autor: María del Carmen Martín Buro (UPM)
  • Autor: Fernando Maestu Unturbe (UPM)
Research Group, Departaments and Institutes related
  • Creador: Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
S2i 2019 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)