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Memorias de investigación
Artículos en revistas:
Test-retest reliability of resting-state magnetoencephalography power in sensor and source space
Año:2016
Áreas de investigación
  • Tecnología electrónica y de las comunicaciones
Datos
Descripción
Several studies have reported changes in spontaneous brain rhythms that could be used as clinical biomarkers or in the evaluation of neuropsychological and drug treatments in longitudinal studies using magnetoencephalography (MEG). There is an increasing necessity to use these measures in early diagnosis and pathology progression; however, there is a lack of studies addressing how reliable they are. Here, we provide the first test-retest reliability estimate of MEG power in resting-state at sensor and source space. In this study, we recorded 3 sessions of resting-state MEG activity from 24 healthy subjects with an interval of a week between each session. Power values were estimated at sensor and source space with beamforming for classical frequency bands: delta (2?4 Hz), theta (4?8 Hz), alpha (8?13 Hz), low beta (13?20 Hz), high beta (20?30 Hz), and gamma (30?45 Hz). Then, test-retest reliability was evaluated using the intraclass correlation coefficient (ICC). We also evaluated the relation between source power and the within-subject variability. In general, ICC of theta, alpha, and low beta power was fairly high (ICC?>?0.6) while in delta and gamma power was lower. In source space, fronto-posterior alpha, frontal beta, and medial temporal theta showed the most reliable profiles. Signal-to-noise ratio could be partially responsible for reliability as low signal intensity resulted in high within-subject variability, but also the inherent nature of some brain rhythms in resting-state might be driving these reliability patterns. In conclusion, our results described the reliability of MEG power estimates in each frequency band, which could be considered in disease characterization or clinical trials
Internacional
Si
JCR del ISI
Si
Título de la revista
Human Brain Mapping
ISSN
1065-9471
Factor de impacto JCR
4,962
Información de impacto
Volumen
37
DOI
10.1002/hbm.23027
Número de revista
1
Desde la página
179
Hasta la página
190
Mes
OCTUBRE
Ranking
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: María del Carmen Martín Buro (UPM)
  • Autor: Fernando Maestu Unturbe (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
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