Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Adaptation of a sterilizing plant virus: tuning virulence and resource exploitation
Year:2017
Research Areas
  • Virology,
  • Crop production
Information
Abstract
Although the fate of parasites is often determined by its ability for adapting to its host(s), little is known on the mechanisms and determinants of host adaptation. This is especially so for sterilizing parasites, which may have devastating effects on host populations as they prevent host reproduction. Theory predicts that sterilizing parasites would evolve towards absolute host sterilization and lower virulence to optimize resource exploitation. However, this hypothesis has seldom been analysed experimentally. We investigated host adaptation processes of the sterilizing plant virus Turnip mosaic virus (TuMV) to its natural host Arabidopsis thaliana by serial passage experiments. After passaging, we quantified virus accumulation, effect on plant growth and development, and virulence of the ancestral and passaged viral genotypes in A. thaliana. Results indicated that passaging increased the proportion of infected plants showing absolute sterility, reduced TuMV virulence, and increased virus multiplication, therefore resulting in host adaptation. Genomic comparison of the ancestral and passaged TuMV genotypes mapped candidate genetic determinants of host adaptation in viral proteins (P1, P3, and 6K2) with host-dependent functions. Thus, our results support theoretical predictions, and contribute to better understand the phenotypic and genetic changes leading to host adaptation.
International
Si
Congress
9th Workshop in Virus Evolution
960
Place
Toftrees Cnference Center; State College, PA, USA
Reviewers
Si
ISBN/ISSN
000-00-0000-000-0
Start Date
09/03/2017
End Date
12/03/2017
From page
7
To page
7
Abstracts
Participants
  • Autor: Viji Vijayan . (UPM)
  • Autor: Silvia López González (UPM)
  • Autor: Flora Sanchez Sanchez (UPM)
  • Autor: Fernando Ponz Ascaso (UPM)
  • Autor: Jesus Israel Pagan Muñoz (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Patología Vegetal
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
  • Departamento: Biotecnología - Biología Vegetal
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