Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Short-Term Effects of Binaural Beats on EEG Power, Functional Connectivity, Cognition, Gait and Anxiety in Parkinson?s Disease
Year:2017
Research Areas
  • Eeg/ evoke potencials,
  • Cognitive neuroscience,
  • Insanity senile (alzheimer, parkinson),
  • Engineering
Information
Abstract
We applied rhythmic binaural sound to Parkinson?s Disease (PD) patients to investigate its influence on several symptoms of this disease and on Electrophysiology (Electrocardiography and Electroencephalography (EEG)). We conducted a double-blind, randomized controlled study in which rhythmic binaural beats and control were administered over two randomized and counterbalanced sessions (within-subjects repeated-measures design). Patients (n=14, age 62±6.1, stage I?III Hoehn & Yahr scale) participated in two sessions of sound stimulation for 10min separated by a minimum of 7 days. Data were collected immediately before and after both stimulations with the following results: (1) a decrease in theta activity, (2) a general decrease in Functional Connectivity (FC), and (3) an improvement in working memory performance. However, no significant changes were identified in the gait performance, heart rate or anxiety level of the patients. With regard to the control stimulation, we did not identify significant changes in the variables analyzed. The use of binaural-rhythm stimulation for PD, as designed in this study, seems to be an effective, portable, inexpensive and noninvasive method to modulate brain activity. This influence on brain activity did not induce changes in anxiety or gait parameters; however, it resulted in a normalization of EEG power (altered in PD), normalization of brain FC (also altered in PD) and working memory improvement (a normalizing effect). In summary, we consider that sound, particularly binaural-rhythmic sound, may be a co-assistant tool in the treatment of PD, however more research is needed to consider the use of this type of stimulation as an effective therapy.
International
Si
JCR
Si
Title
International Journal of Neural Systems
ISBN
0129-0657
Impact factor JCR
6,333
Impact info
Datos JCR del año 2016
Volume
28
10.1142/S0129065717500551
Journal number
5
From page
1
To page
16
Month
SIN MES
Ranking
Q1
Participants
  • Autor: Gerardo Miguel Galvez Garcia (UPM)
  • Autor: Manuel Recuero Lopez (UPM)
  • Autor: Leonides Canuet Delis (UPM)
  • Autor: Francisco del Pozo Guerrero (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Investigación en Instrumentación y Acústica Aplicada (I2A2)
  • Departamento: Ingeniería Mecánica
  • Departamento: Tecnología Fotónica y Bioingeniería
S2i 2019 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)