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Descripción
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| The central dogma of biology, in the simplest version, comprises two stages, transduction and translation, translating non-functional DNA information into an operational form represented by a protein. In this paper we simulated the optimization of the parameters that regulate genetic expression being the main contribution the proposal of the evolutionary surface of the parameters space. In particular we are referring to the production and degradation rates of mRNA and proteins. In addition, some methodological suggestions are made on how to study the regulation of genetic expression and on the different ways of reporting the results, either through bacterial agents or via differential equations. This work may be relevant in synthetic biology, bioinformatics or artificial life, as well as other areas of research. | |
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Internacional
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Si |
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JCR del ISI
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No |
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Título de la revista
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International Journal Information Models and Analyses |
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ISSN
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1314-6416 |
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Factor de impacto JCR
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Información de impacto
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Volumen
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7 |
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DOI
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Número de revista
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2 |
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Desde la página
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3 |
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Hasta la página
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13 |
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Mes
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SIN MES |
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Ranking
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