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Memorias de investigación
Ponencias en congresos:
Biomarkers of Neurodegenerative Progression from Spontaneous Speech Recorded in Mobile Devices: An Approach based on Articulation Speed Estimation - A Study of Patients Suffering from Amyotrophic Lateral Sclerosis
Año:2018
Áreas de investigación
  • Bioinstrumentación
Datos
Descripción
A majority of patients with Amyotrophic Lateral Sclerosis (ALS) experiment a rapid evolution of symptoms related to a progressive decline in movement function that affects different systems. Clinical assessment is based on measures of progression for identifying the need and the pace of medical decisions, and to measure also the effects of novel therapies. But assessment is limited to the periodicity of clinical appointments that are increasingly difficult for patients due to progressive mobility impairments. In this paper, we present a novel method to assess neurodegeneration process through speech analysis. An articulation kinematic model is proposed to identify markers of neuromotor functional progression in speech. We analysed speech samples that were collected with a mobile device, in 3-month intervals, from a group of six subjects with ALS. Results suggest that the method proposed is sensitive to the symptoms of the disease, as rated by observational clinical scales, and it may contribute to assist clinicians and researchers with better and continuous measures of disease progression.
Internacional
Si
Nombre congreso
11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018)
Tipo de participación
960
Lugar del congreso
Santa Cruz, Madeira, Portugal
Revisores
Si
ISBN o ISSN
978-989-758-279-0
DOI
10.5220/0006731302690275
Fecha inicio congreso
19/01/2018
Fecha fin congreso
21/01/2018
Desde la página
269
Hasta la página
275
Título de las actas
Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - Volume 4: BIOSIGNALS
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Ana Rita Londral (Universidade de Lisboa)
  • Autor: Pedro Gomez Vilda (UPM)
  • Autor: Andres Gomez Rodellar (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Informática Aplicada al Procesado de Señal e Imagen
  • Grupo de Investigación: Investigación en Instrumentación y Acústica Aplicada (I2A2)
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Arquitectura y Tecnología de Sistemas Informáticos
  • Departamento: Ingeniería Mecánica
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