Descripción
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The major milk allergen Bos d 5 is a lipocalin and can be loaded with quercetin, a flavonoid with a great affinity to iron. We previously demonstrated in vitro that the loading of Bos d 5 with such a ligand is decisive for induction of immune tolerance. Here, we addressed the in vivo relevance of this observation by nasal allergic sensitization of BALB/c mice using unloaded (apo?) or quercetin?iron?loaded (holo?) Bos d 5, and further elucidated a potential mechanistic role of the aryl hydrocarbon receptor (AhR) pathway. | |
Internacional
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Si |
Nombre congreso
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European Academy of Allergy and Clinical Immunology (EAACI), congress 2018. |
Tipo de participación
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960 |
Lugar del congreso
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Revisores
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Si |
ISBN o ISSN
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0105-4538 |
DOI
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Fecha inicio congreso
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26/05/2018 |
Fecha fin congreso
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30/05/2018 |
Desde la página
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17 |
Hasta la página
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17 |
Título de las actas
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Special Issue:Abstracts from the European Academy of Allergy and Clinical Immunology Congress, 26?30 May 2018, Munich, Germany |