Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
PIN-LIKES Coordinate Brassinosteroid Signaling with Nuclear Auxin Input in Arabidopsis thaliana
Año:2019
Áreas de investigación
  • Aplicaciones a ciencias geológicas y biológicas,
  • Ecuaciones diferenciales,
  • Ciencias biológicas,
  • Botánica
Datos
Descripción
Auxin and brassinosteroids (BR) are crucial growth regulators and display overlapping functions during plant development. Here, we reveal an alternative phytohormone crosstalk mechanism, revealing that BR signaling controls PIN-LIKES (PILS)-dependent nuclear abundance of auxin. We performed a forward genetic screen for imperial pils (imp) mutants that enhance the overexpression phenotypes of PILS5 putative intracellular auxin transport facilitator. Here, we report that the imp1 mutant is defective in the BR-receptor BRASSINOSTEROID INSENSITIVE 1 (BRI1). Our set of data reveals that BR signaling transcriptionally and post-translationally represses the accumulation of PILS proteins at the endoplasmic reticulum, thereby increasing nuclear abundance and signaling of auxin. We demonstrate that this alternative phytohormonal crosstalkmechanism integrates BR signaling into auxin-dependent organ growth rates and likely has widespread importance for plant development
Internacional
Si
JCR del ISI
Si
Título de la revista
Current Biology
ISSN
0960-9822
Factor de impacto JCR
9,601
Información de impacto
Volumen
DOI
10.1016/j.cub.2020.02.002
Número de revista
Desde la página
1579
Hasta la página
1588
Mes
SIN MES
Ranking
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Lin Sun (Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences (BOKU))
  • Autor: Elena Feraru ((Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences (BOKU)))
  • Autor: Mugurel Feraru (Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences (BOKU)
  • Autor: Sascha Waidmann (Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences (BOKU))
  • Autor: Wenfei Wang (Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA)
  • Autor: Gisele Passaia (Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA)
  • Autor: Zhi-Yong Wang (Department of Plant Biology, Carnegie Institution for Science, Stanford, CA 94305, USA)
  • Autor: Krzysztof Wabnik (UPM)
  • Autor: Jurgen Kleine-Vehn (Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences (BOKU))
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Biotecnología Vegetal
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
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