Research Publications in journals:
Label-free optical biosensing with slot-waveguides.
We demonstrate label-free molecule detection by using an integrated biosensor based on a Si3N4 /SiO2 slotwaveguide
microring resonator. Bovine serum albumin (BSA) and anti-BSA molecular binding events on the
sensor surface are monitored through the measurement of resonant wavelength shifts with varying biomolecule
concentrations. The biosensor exhibited sensitivities of 1.8 and 3.2 nm/ ng/mm2 for the detection of
anti-BSA and BSA, respectively. The estimated detection limits are 28 and 16 pg/mm2 for anti-BSA and
BSA, respectively, limited by wavelength resolution.