Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Optimization of Sub-micro-holes 2D periodic interferometric structures for biochemical sensing based on advance high sensitivity optical techniques
Year:2008
Research Areas
  • Fluid mechanics,
  • Polymers,
  • Electronics engineering,
  • Naval engineering,
  • Magnetic materials
Information
Abstract
The integration between micro-nano fluidics and optics is a new emerging research field, with promising high impact applications in the area of optical biosensing devices. This is the case of tunable Mach-Zehnder interferometers, photonic crystals and ring resonators, which have been demonstrated recently. Recent investigations have demonstrated that by combination of the simultaneous used of Ellipsometry, Reflectometry and Spectrometry based technologies broadly used in semiconductor industry at sub-micron spot-size level and advanced photonic structures, a relevant improvement can be achieved at the level of performance of the current state of the art for label-free biosensing and nano-fluidics metrology. The variation in the effective index of refraction can be easily detected in micron/sub-micron domains due to the fact of using several reflectivity profiles and optical responses simultaneously, making possible to remove ambiguities in the sensing interrogation process. To achieve this novel bio-chemical sensing system, it is proposed to combine the miniaturization of sub-micro-holes based Interferometric photonic structures in combination with sub-micron spot size advance optical techniques holistically. Thus, optical sensing system is based on the observation of external reflectivity profile of the high sensitive photonic structures. The reflectivity profile provides four magnitudes which can be used to assess the photonic structures response proposed in this project. These are the reflected amplitude and phase of the electric field components polarised parallel (p) and perpendicular (s) to the plane incidence. The reflected light of the photonic structures produce spectra interference patterns as a function of the angle of incidence for p and s polarisation directions and as a function of the spectral range. These patterns are the fundamental source of information to detect the biomolecules binding in the sensing surfaces, ultra small fraction of volumes and flow control in sub-micron domains. Theoretical calculations at CLUPM demonstrate that a detection limit of 10-7 R.I.U. and surface concentration detection limit of 0.1 pg/mm2 are feasible.
International
Si
Congress
E-MRS SPRING MEETING 2008. SYMPOSIUM C
960
Place
Estrasburgo (Francia)
Reviewers
Si
ISBN/ISSN
0000000000
Start Date
26/05/2008
End Date
30/05/2008
From page
1
To page
1
ABSTRACTS WEB EMRS
Participants
  • Autor: Rafael Casquel Del Campo (UPM)
  • Autor: Jose Luis Ocaña Moreno (UPM)
  • Autor: Carlos Luis Molpeceres Alvarez (UPM)
  • Autor: Miguel Holgado Bolaños (UPM)
  • Autor: Miguel Morales Furio (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Ingeniería y Aplicaciones del Láser
  • Centro o Instituto I+D+i: Centro Laser
  • Departamento: Física Aplicada a la Ingeniería Industrial
S2i 2019 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)