Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Functional interaction between the NADPH oxidasa and heterotrimeric G proteins in the pathogen response
Research Areas
  • Molecular biology,
  • Crop production
The Rboh genes (Respiratory burst oxidase homologs) from the plant NADPH oxidase are responsible for the production of reactive oxygen species (ROS) in response to pathogens and other responses to the environment (Torres et al., 2005). In response to ozone, there is also a production of ROS similar to the pathogen response, where the Rboh and heterotrimeric G proteins have been implicated (Joo et al., 2005) Our goal is to characterize the functional interaction between the Arabidopsis Atrboh and the heterotrimeric G proteins in the context of the pathogen response. We performed epistasis studies between the NADPH oxidase mutants atrbohD and atrbohF and mutants in the ¿ (gpa1-4) and ß (agb1-2) subunits of the heterotrimeric G proteins. We observe that agb1-2 suppresses the mutant phenotypes in the atrboh in response to bacteria and the oomycete Hyaloperonospora Arabidopsis (Torres et al., 2002). This positions the heterotrimeric G proteins downstream of the Atrboh. However, agb1-2 and the atrboh show an additive effect on susceptibility to the necrotrophic fungus Plectosphaerella cucumerina, which suggest two different pathways. There is, therefore, a complex relationship between the signaling of ROS produced by NADPH oxidase and the heterotrimeric G proteins, where the functional interaction between these regulatory systems varies depending on the context of the pathogen.
XIV International Congress International Society Molecular Plant Microbe Interactions 2009.
Quebec City (Canada)
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XIV International Congress International Society Molecular Plant Microbe Interactions 2009.
  • Participante: Jeffery Dangl (University of North Carolina)
  • Autor: Miguel Angel Torres Lacruz (UPM)
  • Participante: Alan Jones (University of North Carolina)
  • Autor: Clara Sánchez Rodríguez (UPM)
  • Autor: Antonio Molina Fernandez (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Patología Vegetal
  • Grupo de Investigación: Interacciones Moleculares Planta-Patógeno
  • Departamento: Biotecnología
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)