Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Assessment of 3D DCE-MRI of the kidneys using non-rigid image registration and segmentation of voxel time courses
Year:2009
Research Areas
  • Electronics engineering
Information
Abstract
We have applied automated image analysis methods in the assessment of human kidney perfusion based on 3D dynamic contrast-enhanced MRI data. This approach consists of non-rigid 3D image registration of the moving kidney followed by k-means clustering of the voxel time courses with split between left and right kidney. This method was applied to four data sets acquired from healthy volunteers, using 1.5 T (2 exams) and 3 T scanners (2 exams). The proposed registration method reduced motion artifacts in the image time series and improved further analysis of the DCE-MRI data. The subsequent clustering to segment the kidney compartments was in agreement with manually delineations (similarity score of 0.96) in the same motion corrected images. The resulting mean intensity time curves clearly show the successive transition of contrast agent through kidney compartments (cortex, medulla, and pelvis). The proposedmethod formotion correction and kidneycompartment segmentation mightimprove the validity and usefulness of further model-based pharmacokinetic analysis of kidney function in patients.
International
Si
JCR
Si
Title
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
ISBN
0895-6111
Impact factor JCR
1,192
Impact info
Volume
33
10.1016/j.compmedimag.2008.11.004
Journal number
0
From page
171
To page
181
Month
ABRIL
Ranking
Participants
  • Autor: Rosario Sance Garzón (UPM)
  • Autor: Maria Jesus Ledesma Carbayo (UPM)
  • Autor: Andres de Santos Lleo (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Tecnología de imágenes biomédicas
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Departamento: Ingeniería Electrónica
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)