Observatorio de I+D+i UPM

Memorias de investigación
Research Publications in journals:
Arabidopsis DOF transcription factors act redundantly to reduce CONSTANS expression and are essential for a photoperiodic flowering response.
Year:2009
Research Areas
  • Molecular biology
Information
Abstract
Abstract Flowering of Arabidopsis is induced by long summer days (LDs). The transcriptional regulator CONSTANS (CO) promotes flowering, and its transcription is increased under LDs. We systematically misexpressed transcription factors in companion cells and identified several DOF proteins that delay flowering by repressing CO transcription. Combining mutations in four of these, including CYCLING DOF FACTOR 2 (CDF2), caused photoperiod-insensitive early flowering by increasing CO mRNA levels. CO transcription is promoted to differing extents by GIGANTEA (GI) and the F-box protein FKF1. We show that GI stabilizes FKF1, thereby reducing CDF2 abundance and allowing transcription of CO. Despite the crucial function of GI in wild-type plants, introducing mutations in the four DOF-encoding genes into gi mutants restored the diurnal rhythm and light inducibility of CO. Thus, antagonism between GI and DOF transcription factors contributes to photoperiodic flowering by modulating an underlying diurnal rhythm in CO transcript levels.
International
Si
JCR
Si
Title
DEVELOPMENTAL CELL
ISBN
1534-5807
Impact factor JCR
12,882
Impact info
Volume
Journal number
0
From page
75
To page
86
Month
ENERO
Ranking
Participants
  • Participante: F Fornara
  • Participante: N Sauerbrunn
  • Participante: M Rühl
  • Autor: Jose Antonio Jarillo Quiroga (UPM)
  • Participante: G Coupland
  • Participante: KC Panigrahi
  • Participante: L Gissot
Research Group, Departaments and Institutes related
  • Creador: Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)