Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Functional interaction between the NADPH oxidasa and heterotrimeric G proteins in the pathogen response.
Year:2009
Research Areas
  • Molecular biology
Information
Abstract
The Rboh genes (Respiratory burst oxidase homologs) from the plant NADPH oxidase are responsible for the production of reactive oxygen species (ROS) in response to pathogens and other responses to the environment (Torres et al., 2005). In response to ozone, there is also a production of ROS similar to the pathogen response, where the Rboh and heterotrimeric G proteins have been implicated (Joo et al., 2005) Our goal is to characterize the functional interaction between the Arabidopsis Atrboh and the heterotrimeric G proteins in the context of the pathogen response. We performed epistasis studies between the NADPH oxidase mutants atrbohD and atrbohF and mutants in the ¿ (gpa1-4) and ß (agb1-2) subunits of the heterotrimeric G proteins. We observe that agb1-2 suppresses the mutant phenotypes in the atrboh in response to bacteria and the oomycete Hyaloperonospora Arabidopsis (Torres et al., 2002). This positions the heterotrimeric G proteins downstream of the Atrboh. However, agb1-2 and the atrboh show an additive effect on susceptibility to the necrotrophic fungus Plectosphaerella cucumerina, which suggest two different pathways. There is, therefore, a complex relationship between the signaling of ROS produced by NADPH oxidase and the heterotrimeric G proteins, where the functional interaction between these regulatory systems varies depending on the context of the pathogen.
International
Si
Congress
Plant ROS 2009
960
Place
Helsinki, Finlandia
Reviewers
Si
ISBN/ISSN
0000-0000
Start Date
08/09/2009
End Date
10/09/2009
From page
37
To page
37
LIBRO DE RESUMENES
Participants
  • Participante: J. L. Dangl
  • Autor: Clara Sánchez Rodríguez (UPM)
  • Autor: Antonio Molina Fernandez (UPM)
  • Autor: Miguel Angel Torres Lacruz (UPM)
Research Group, Departaments and Institutes related
  • Creador: Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
  • Departamento: Biotecnología
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