|
Descripción
|
|
|---|---|
| Progression through the different phases of cell division requires the specific degradation of proteins through the ubiquitin-proteasome 265 (Ub/26S) pathway. In plants, this pathway plays a key role in controlling several developmental processes and responses, including cell proliferation. SKP2A is an F-box protein that forms an SCF complex in vivo with E3 ubiquitin ligase activity. SKP2A positively regulates cell division, at least, in part, by degrading the E2FC/DPB transcription repressor. Plants that over-express SKP2A increase the number of cells in G2/M, reduce the level of ploidy and develop higher number of lateral root primordia. Despite of the high degree of similarity between of SKP2A and SKP2B, we have found that they show target specifiCity, since SKP2A, but not SKP2B, targets DPB for degradation. We are mapping the regions of SKP2A that are required for DPB targeting by deleting different regions of the C-terminus of SKP2A. | |
|
Internacional
|
Si |
|
Nombre congreso
|
2nd EMBO CONFERENCE ON PLANT MOLECULAR BIOLOGY "FRONTIERS OF PLANT RESEARCH" |
|
Tipo de participación
|
960 |
|
Lugar del congreso
|
CADIZ. ESPAÑA |
|
Revisores
|
Si |
|
ISBN o ISSN
|
0000-0000 |
|
DOI
|
|
|
Fecha inicio congreso
|
06/05/2009 |
|
Fecha fin congreso
|
09/05/2009 |
|
Desde la página
|
116 |
|
Hasta la página
|
116 |
|
Título de las actas
|
LIBRO DE RESUMENES |