Observatorio de I+D+i UPM

Memorias de investigación
Communications at congresses:
Plant innate immunity at the cell wall and beyond
Year:2010
Research Areas
  • Molecular, cellular and genetic biology
Information
Abstract
The cell wall provides a passive barrier against pathogens and pests, constitutes a reservoir of antimicrobial compounds and is a source of signalling molecules. During plant development or microbial infection cell-wall perturbations occur that lead to changes in gene expression. The characterization of plant resistance to necrotrophic and vascular pathogens has revealed the relevance of cell wall in the regulation of Arabidopsis thaliana immune responses. To determine the relevance of cell wall in plant innate immunity, biased resistance screenings of Arabidopsis cell wall mutants were performed in our labs, and novel signal transduction pathways and regulatory proteins controlling plant innate immune response to different types of pathogens were identified. Among these regulatory proteins was ERECTA, a Receptor-Like-Kinases (RLKs), that control plant development and resistance to some type of pathogens. To identify new elements of ER-mediated immunity, a genetic screen was conducted in a mutagenized population of the highly susceptible er-1 mutant to find suppressors of erecta susceptibility (ser) to the necrotrophic fungus P. cucumerina. Comparative analyses of the cell wall composition/structure of er-1 and ser1 and ser2 isolated highlighted the relevance in disease resistance of these metrics, indicating that cell wall composition is a determinant of fungal colonization success. The genetic interaction among these novel components of plant innate immunity as well as the recent data describing the characterization of the specific interconnection between cell wall integrity and activation of immune response will be presented.
International
Si
Congress
XII Cell Wall Meeting
960
Place
Oporto (Portugal)
Reviewers
Si
ISBN/ISSN
978-84-693-4612-9
Start Date
25/07/2010
End Date
29/07/2010
From page
50
To page
50
XII Cell Wall Meeting
Participants
  • Autor: Antonio Molina Fernandez (UPM)
  • Autor: Andrea Sánchez Vallet (UPM)
Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Interacciones Moleculares Planta-Patógeno
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
S2i 2020 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)