SFS is a versatile and inexpensive production method for fibroin-based biomaterials to produce fibers that combine biocompatibility and high performance
A novel spinning system allows the production of protein fibers under a wide range of conditions, leading to biomaterials with properties that can be tailored for their intended use. Its application to silk fibroin endows the natural material with additional advantages that make it extremely well suited as scaffolding biomaterial for the treatment of tendon and ligament pathologies that demand short-term high mechanical performance along with utmost biocompatibility and cell interaction.
A novel spinning technology (SFS) allows the spinning of protein fibers through an inexpensive and environmentally friendly procedure that enables adapting the material to its intended use.
Fibroin obtained from silkworm silk is processed into fibers exhibiting the excellent properties of the natural silks (biocompatibility and high performance) and are endowed with emergent properties such as mechanical pre-stressing and biological activity. This new combination of properties makes them ideal for applications in Medicine that range from sutures to scaffolding bioactive biomaterials for cell therapies and Tissue Engineering. In particular, these fibers are especially suited to treatments on diseased or injured tendons and ligaments, where the mechanical performance at early stages is critical.
“Biocompatible and bioactive high-performance biomaterials can be used in a wide range of orthopaedic therapies, increasing healing chances and decreasing convalescence time”
“An adequate solution for the therapy of diseased or injured tendons and ligaments that prevents the usage of grafts is missing”
José Pérez Rigueiro; e: firstname.lastname@example.org
Gustavo V. Guinea; e: email@example.com
Centro de Tecnología Biomédica-UPM
Innovation, Commercialization and Entrepreneurship Area
Centre of Support for Technological Innovation – UPM