Proyecto de I+D+i:
OXYREG: Regulation of the production of reactive oxygen species by the plant NADPH oxidase and its role in pathogen response and in response to other environmental or developmental factors
Áreas de investigación
The production of Reactive Oxygen Species (ROS) is one of the earlier responses observed after pathogen infection in plants. It is becoming evident that ROS are not direct killers but signals that mediate the activation of the plant defences as well as other responses to the environment, developmental processes and Programmed Cell Death (PCD). This topic is of such importance in plant biology that it was recently the subject of a Special Issue in Plant Physiology (June, 2006), were the importance of the NADPH oxidase was specially outlined.
Plants use ROS-derived signals in a variety of developmental contexts and in response to both biotic and abiotic stress. It is hence important to understand the signalling controls that allow plant cells to interpret ROS-dependent signals. Our goal is to decipher, using functional genomics tools, the functions of the plant NADPH oxidase gene family. Different members of the rboh (respiratory burst oxidase homologues) family, components of the plant NADPH oxidase, control production of ROS during defence and other responses. We will perform this research in Arabidopsis, model organism for studies in plants, where many genomic tools are available. We intend to further the identification of the factors that regulate Atrboh function, as well as putative targets or mediators of ROS-dependent signalling.
It has been suggested that phosphorylation events and Ca++ signalling are implicated in this regulation. In addition, many evidences suggest the existence of a crosstalk between ROS and other signalling molecules like salicylic acid (SA) and abscisic acid (ABA). We are particularly interested in the signalling interaction between ROS and heterotrimeric G proteins that mediate responses like pathogen defence and stomata closure. These studies will allow us to further understand the function of ROS not only in disease resistance, but also in other responses to the environment and developmental processes.
Tipo de proyecto
Proyectos y convenios en convocatorias públicas competitivas
Tamaño de la entidad
Esta actividad pertenece a memorias de
Director: Miguel Angel Torres Lacruz (UPM)
Participante: Begoña Prieto Garcia (UPM)
Participante: Jorge Morales Bello (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
Creador: No seleccionado
Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP