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Descripción
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| Fibromyalgia is a syndrome characterized by chronic widespread pain and reduced pain thresholds during somatosensory stimulation. The existence of central pain augmentation in this condition is evidenced by the fact that, when subjected to the same amount of stimulation, patients show enhanced brain responses as compared to controls. In the present work, magnetoencephalography was used to obtain brain responses to mechanical pressure both above and below the pain threshold. Activity was recorded from 9 patients and 9 control subjects using a purpose-built stimulator. The amount of pressure was adjusted to produce similar subjective levels of pain in both groups. The comparison of differences between brain responses evoked by stimulation above and below the pain threshold revealed increases in amplitude in somatosensory, temporal, parietal and prefrontal areas at short latencies and in prefrontal areas at long latencies in favour of patients as compared to control subjects. Therefore, in addition to showing increased responses when the objective level of stimulation is kept the same as for control subjects, fibromyalgia patients show central pain augmentation after adjusting the amount of pressure to produce similar subjective levels of pain in both groups. | |
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Internacional
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Si |
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Nombre congreso
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8th FENS Forum of Neuroscience |
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Tipo de participación
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960 |
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Lugar del congreso
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BARCELONA |
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Revisores
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Si |
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ISBN o ISSN
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DOI
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Fecha inicio congreso
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14/07/2012 |
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Fecha fin congreso
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18/07/2012 |
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1 |
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1 |
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Título de las actas
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