Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
Ecdysteroid receptor docking suggests that dibenzoylhydrazine-based insecticides are devoid to any deleterious effect on the parasitic wasp Psyttalia concolor (Hym. Braconidae).
Año:2012
Áreas de investigación
  • Producción vegetal
Datos
Descripción
BACKGROUND: The moulting accelerating compounds (MACs) or ecdysteroid agonists represent a selective group of insecticides acting upon binding to the ecdysteroid receptor (EcR) and leading to lethal premature moulting in larval stages and aborted reproduction in adults. Psyttalia concolor Szèpl. is a useful parasitic wasp attacking important tephritid pests such as the medfly and olive fruit fly. RESULTS: Contact and oral exposure in the laboratory of female parasitic wasps to the dibenzoylhydrazine-based methoxyfenozide, tebufenozide and RH-5849 did not provoke negative effects. No mortality and no reduction in beneficial capacity were observed. The ligand-binding domain (LBD) of the EcR of P. concolor was sequenced, and a homology protein model was constructed which confirmed a cavity structure with 12 ?-helices, harbouring the natural insect moulting hormone 20-hydroxyecdysone. However, a steric clash occurred for the MAC insecticides owing to a restricted extent of the ligand-binding cavity of the PcLBD-EcR, while they did dock well in that of susceptible insects. CONCLUSIONS: The insect toxicity assays demonstrated that MACs are selective for P. concolor. The modelling/docking experiments are indications that these insecticides do not bind with the LBD-EcR of P. concolor and support the theory that they show no biological effects in the parasitic wasp. These data may help in explaining the compatible use of MACs together with parasitic wasps in IPM programmes. Copyright © 2012 Society of Chemical Industry
Internacional
Si
JCR del ISI
Si
Título de la revista
Pest Management Science
ISSN
1526-498X
Factor de impacto JCR
2,251
Información de impacto
Volumen
68
DOI
10.1002/ps.3274
Número de revista
7
Desde la página
976
Hasta la página
985
Mes
SIN MES
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Participantes
  • Autor: Paloma Bengochea
  • Autor: Olivier Christiaens
  • Autor: Fermín Amor Parrilla (UPM)
  • Autor: Elisa Viñuela Sandoval (UPM)
  • Autor: Pierre Rougé
  • Autor: Maria Pilar Medina Velez (UPM)
  • Autor: Guy Smagghe
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Manejo Integrado de Plagas
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