Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
Insect growth regulators as potential insecticides to control olive fruit fly (Bactrocera oleae Rossi): insect toxicity bioassays and molecular docking approach
Año:2012
Áreas de investigación
  • Producción vegetal
Datos
Descripción
BACKGROUND: Olive fruit fly, Bactrocera oleae (Rossi), is a key pest in olive orchards, causing serious economic damage. To date, the pest has already developed resistance to the insecticides commonly applied to control it. Thus, in searching for new products for an accurate resistance management programme, targeting the ecdysone receptor (EcR)might provide alternative compounds for use in such programmes. RESULTS: Residual contact and oral exposure in the laboratory of B. oleae adults to the dibenzoylhydrazine-based compounds methoxyfenozide, tebufenozide and RH-5849 showed different results. Methoxyfenozide and tebufenozide did not provoke anynegative effectsontheadults,but RH-5849 killed98-100%of the treated insects15 days after treatment. Theligand-binding domain (LBD) of the EcR of B. oleae (BoEcR-LBD) was sequenced, and a homology protein model was constructed. Owing to a restricted extent of the ligand-binding cavity of the BoEcR-LBD, docking experiments with the three tested insecticides showed a severe steric clash in the case of methoxyfenozide and tebufenozide, while this was not the case with RH-5849. CONCLUSION: IGR molecules similar to the RH-5849 molecule, and different from methoxyfenozide and tebufenozide, might have potential in controlling this pest.
Internacional
Si
JCR del ISI
Si
Título de la revista
Pest Management Science
ISSN
1526-498X
Factor de impacto JCR
2,251
Información de impacto
Volumen
69
DOI
10.1002/ps.3350
Número de revista
Desde la página
27
Hasta la página
34
Mes
JUNIO
Ranking
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Paloma Bengochea
  • Autor: Olivier Christiaens
  • Autor: Fermín Amor Parrilla (UPM)
  • Autor: Elisa Viñuela Sandoval (UPM)
  • Autor: Pierre Rougé
  • Autor: Maria Pilar Medina Velez (UPM)
  • Autor: Guy Smagghe
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Manejo Integrado de Plagas
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