Observatorio de I+D+i UPM

Descripción
The understanding of the processes underlying embryo development from a single cell into a multicellular organism is a longterm goal of Development Biology that is recently being feasible thanks to the availability of massive 3D+t complex data acquired with new microscopy technologies. But these large quantities of data require automated or semi-automated image processing methods to be possible. Current developments and challenges in biological image processing include algorithms for microscopy multiview fusion, cell nucleus tracking for lineage reconstruction, cell segmentation, multidimensional image registration and gene expression atlases. These tools are to eventually produce in toto reconstruction of the embryo development combining the cell lineage tree with quantitative gene expression data in its spatio-temporal context. ln this work several processing tools developed by our group will be presented: like a multiview image fusion for Light-Sheet Fluorescence Microscopy , a cell lineage reconstruction workflow for early stages of embryo development ] and on-going work on the construction of gene expression atlases of embryogenesis.
Internacional	Si
ISSN o ISBN	.
Entidad relacionada	Universitat de Barcelona
Nacionalidad Entidad	ESPAÑA
Lugar del congreso	Barcelona, España

Esta actividad pertenece a memorias de investigación

• Autor: Andres de Santos Lleo (UPM)

• Creador: Grupo de Investigación: Tecnología de imágenes biomédicas