Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
Age-Related Effects in Working Memory Recognition Modulated by Retroactive Interference
Año:2012
Áreas de investigación
  • Biomedicina
Datos
Descripción
One of the main causes for age-related declines in working memory is a higher vulnerability to retroactive interference due to a reduced ability to suppress irrelevant information. However, the underlying neural correlates remain to be established. Magnetoencephalography was used to investigate differential neural patterns in young and older adults performing an interference-based memory task with two experimental conditions, interrupting and distracting, during successful recognition. Behaviorally, both types of retroactive interference significantly impaired accuracy at recognition more in older adults than in young adults with the latter exhibiting greater disruptions by interrupters. Magnetoencephalography revealed the presence of differential age-related neural patterns. Specifically, time-modulated activations in temporo-occipital and superior parietal regions were higher in young adults compared with older adults for the interrupting condition. These results suggest that age-related deficits in inhibitory mechanisms that increase vulnerability to retroactive interference may be associated with neural under-recruitments in a high-interference task.
Internacional
Si
JCR del ISI
Si
Título de la revista
Journals of Gerontology Series a-Biological Sciences And Medical Sciences
ISSN
1079-5006
Factor de impacto JCR
4,598
Información de impacto
Volumen
67
DOI
10.1093/gerona/glr199
Número de revista
6
Desde la página
565
Hasta la página
572
Mes
JUNIO
Ranking
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Participantes
  • Autor: Javier De Felipe Oroquieta (UPM)
  • Autor: FERNANDO MAESTU UNTURBE (CTB (UCM-UPM))
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
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