Memorias de investigación
Artículos en revistas:
A comparison of quantitative reconstruction techniques for PIXE-tomography analysis applied to biological samples
Año:2014

Áreas de investigación
  • Ingenierías

Datos
Descripción
The tomographic reconstruction of biological specimens requires robust algorithms, able to deal with low density contrast and low element concentrations. At the IST/ITN microprobe facility new GPU-accelerated reconstruction software, JPIXET, has been developed, which can significantly increase the speed of quantitative reconstruction of Proton Induced X-ray Emission Tomography (PIXE-T) data. It has a user-friendly graphical user interface for pre-processing, data analysis and reconstruction of PIXE-T and Scanning Transmission Ion Microscopy Tomography (STIM-T). The reconstruction of PIXE-T data is performed using either an algorithm based on a GPU-accelerated version of the Maximum Likelihood Expectation Maximisation (MLEM) method or a GPU-accelerated version of the Discrete Image Space Reconstruction Algorithm (DISRA) (Sakellariou (2001) [2]). The original DISRA, its accelerated version, and the MLEM algorithm, were compared for the reconstruction of a biological sample of Caenorhabditis elegans ? a small worm. This sample was analysed at the microbeam line of the AIFIRA facility of CENBG, Bordeaux. A qualitative PIXE-T reconstruction was obtained using the CENBG software package TomoRebuild (Habchi et al. (2013) [6]). The effects of pre-processing and experimental conditions on the elemental concentrations are discussed.
Internacional
Si
JCR del ISI
Si
Título de la revista
Nuclear Instruments and Methods in Physics Research Section B: Beam Interact1ons with Materials and Atoms
ISSN
0168-583x
Factor de impacto JCR
Información de impacto
Volumen
331
DOI
10.1016/j.nimb.2014.01.028
Número de revista
Desde la página
248
Hasta la página
252
Mes
SIN MES
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Participantes
  • Autor: D.G. Beasly IST/C2TN, Universidade de Lisboa, Campus Tecnológico e Nuclear
  • Autor: L.C. Alves IST/C2TN, Universidade de Lisboa, Campus Tecnológico e Nuclear
  • Autor: PH. Barberet Univ. Bordeaux, CENBG, UMR, CNRS, IN2P3, CENBG, Francia
  • Autor: S. Bourret Univ. Bordeaux, CENBG, UMR, CNRS, IN2P3, CENBG, Francia
  • Autor: G. Devès Univ. Bordeaux, CENBG, UMR, CNRS, IN2P3, CENBG, Francia
  • Autor: Nuria Gordillo Garcia UPM
  • Autor: C. Michelet Univ. Bordeaux, CENBG, UMR, CNRS, IN2P3, CENBG, Francia
  • Autor: Q. Le Trequesser Univ. Bordeaux, CENBG, UMR, CNRS, IN2P3, CENBG, Institut de Chimie de la Matière Condensée de Bordeaux (ICMCB, UPR9048) CNRS, Université de Bordeaux, Francia
  • Autor: A.C. Marques IST/IPFN, Universidade de Lisboa, Campus Tecnológico e Nuclear
  • Autor: H. Seznec Univ. Bordeaux, CENBG, UMR, CNRS, IN2P3, CENBG, UMR, Francia
  • Autor: R.C. Da Silva IST/IPFN, Universidade de Lisboa, Campus Tecnológico e Nuclear

Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Fusión Nuclear Inercial y Tecnología de fusión
  • Centro o Instituto I+D+i: Instituto de Fusión Nuclear
  • Departamento: Ingeniería Energética