Observatorio de I+D+i UPM

Memorias de investigación
Ponencias en congresos:
Using Parenclitic Networks to Evaluate the Loss of Brain Consistency
Áreas de investigación
  • Física química y matemáticas
Increased variability in performance has been associated with the emergence of several neurological and psychiatric pathologies. However, whether and how consistency of neuronal activity may also be indicative of an underlying pathology is still poorly understood. Here we propose a novel method for evaluating consistency from noninvasive brain recordings. We evaluate the consistency of the cortical activity recorded with magnetoencephalography in a group of subjects diagnosed with Mild Cognitive Impairment (MCI), a condition sometimes prodromal of dementia, during the execution of a memory task. We use metrics coming from nonlinear dynamics to evaluate the consistency of cortical regions. A representation known as Parenclitic Networks is constructed, where atypical features are endowed with a network structure, the topological properties of which can be studied at various scales. Pathological conditions correspond to strongly heterogeneous networks, whereas typical or normative conditions are characterized by sparsely connected networks with homogeneous nodes. The analysis of this kind of networks allows identifying the extent to which consistency is affecting the MCI group and the focal points where MCI is specially severe. To the best of our knowledge, these results represent the first attempt at evaluating the consistency of brain functional activity using complex networks theory.
Nombre congreso
The 10th AIMS Conference on Dynamical Systems, Differential Equations and Applications [http://www.aimsciences.org/conferences/2014/]
Tipo de participación
Lugar del congreso
Fecha inicio congreso
Fecha fin congreso
Desde la página
Hasta la página
Título de las actas
The 10th AIMS Conference on Dynamical Systems Differential Equations and Applications - ABSTRACTS [http://www.aimsciences.org/conferences/2014/abstracts-book-finalized-2014-06-10.pdf]
Esta actividad pertenece a memorias de investigación
  • Autor: Johann Heinz Martínez (UPM)
  • Autor: P. Ariza (Centro de Tecnología Biomédica)
  • Autor: Juan Manuel Pastor Ruiz (UPM)
  • Autor: M. Zanin (Centro de Tecnología Biomédica)
  • Autor: D. Papo (Centro de Tecnología Biomédica)
  • Autor: F. Maestú (Universidad Complutense de Madrid)
  • Autor: R. Bajo (Centro de Tecnología Biomédica)
  • Autor: S. Boccaletti (CNR- Institute for Complex Systems, Italy)
  • Autor: J. M. Buldú (Universidad Rey Juan Carlos)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Grupo de Sistemas Complejos
  • Departamento: Ingeniería Agroforestal
S2i 2021 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)