Memorias de investigación
Communications at congresses:
Postprandial instead of preprandial calibration allows better accuracy of real-time continuous glucose monitoring (CGM)

Research Areas
  • Telematics

Background and aims: The last generation of CGM systems have the advantage of showing glucose data in real-time but their accuracy seem to be worse than the previous CGM systems with retrospective data download. The aim of our study was to find out calibration strategies for improving the agreement of both monitoring systems. Material and methods: Eight patients with type 1 diabetes treated with insulin pumps were requested to use simultaneously the blind CGMS-Gold and the real time Guardian RT from Minimed-Medtronic (72 hours) in 3 different periods. Both needles were placed in the same abdominal side (distance <3cm) and monitor¿s time was synchronised with the pump and the glycometer. The CGMS-Gold was calibrated preprandially along the study while, for the Guardian RT, 3 strategies were tested: 3 pre-meal calibrations, calibration at 1 hour postprandial and, finally, pre- and 1 hour postprandial. The simultaneously measured glucose levels were analysed with Pearson correlation and their mean absolute differences with the Wilcoxon test. Results: Correlation between capillary glucose (used and not used for calibration) and glucose values of the monitor was better for the CGMS-Gold than for the Guardian RT (0.937 vs 0.784). Calibrations including glucose at 1 hour after meals achieved a stronger correlation between Guardian RT and capillary glycemia and also a significant decrease in the mean absolute difference. Conclusions: One-hour postprandial calibration of the Guardian RT achieves a better accuracy than preprandial time. No benefit was shown when adding pre- to postprandial values.
43rd European Association for the Study of Diabetes (EASD) Annual Meeting. Diabetologia 2007; 50 (Supl 1): S419
Amsterdam (Paises Bajos)
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Research Group, Departaments and Institutes related
  • Creador: Grupo de Investigación: Grupo de Bioingeniería y Telemedicina
  • Departamento: Tecnología Fotónica