Observatorio de I+D+i UPM

Memorias de investigación
Ponencias en congresos:
Interactive exploratory data analysis tool in Alzheimer's disease
Año:2015
Áreas de investigación
  • Bioinformática,
  • Ciencias de la computación y tecnología informática
Datos
Descripción
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive cognitive impairment, and a variety of neuropathological changes, which are not homogenous between different brain regions within a given patient or between patients. The availability of techniques to explore the brain provides neuroscientists a wealth of data that is difficult to analyze, as a result of both its volume and its complexity. In order to overcome this problem, we propose to apply a new interactive exploratory data analysis tool, MorExAn (Morphology Exploratory Analyzer), which has been specifically designed to facilitate the study of complex neuroscientific data. In the present study, we used brain tissue from 10 patients with AD (age range 76 - 90 years old). We included quantitative stereological data of several histological features (e.g., neuron and plaques density) obtained from different hippocampal regions, as well as neuropsychological data and common clinical variables. Simultaneous analysis of data using MorExAn allows researchers to immediately detect possible differences between regions and relationships between different types of data. Thus, MorExAn provide us the possibility to relate histopathological data with neuropsychological and clinical variables. The aid of this interactive visualization tool brings us the possibility to find unexpected conclusions beyond the insight provided by simple statistics analysis, as well as to improve neuroscientists? productivity.
Internacional
Si
Nombre congreso
Conference Abstract: B·DEBATE | A Dialogue with the Cerebral Cortex: Cortical Function and Interfacing (Workshop)
Tipo de participación
960
Lugar del congreso
Barcelona, Spain
Revisores
Si
ISBN o ISSN
1662-5137
DOI
10.3389/conf.fnsys.2015.06.00002
Fecha inicio congreso
29/04/2015
Fecha fin congreso
30/04/2015
Desde la página
1
Hasta la página
1
Título de las actas
A Dialogue with the Cerebral Cortex: Cortical Function and Interfacing
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Yulia Diana Furcila . (UPM)
  • Autor: Juan Morales Del Olmo (UPM)
  • Autor: Angel Rodriguez Mtnez.de Bartolome (UPM)
  • Autor: Javier De Felipe Oroquieta (UPM)
  • Autor: Lidia Alonso Nanclares (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Minería de Datos y Simulación (MIDAS)
  • Centro o Instituto I+D+i: Centro de tecnología Biomédica CTB
  • Centro o Instituto I+D+i: Centro de Investigación en Simulación Computacional
  • Departamento: Arquitectura y Tecnología de Sistemas Informáticos
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