Descripción
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Essential tremor (ET) is characterised by postural and action tremors with a frequency of 4-12 Hz. Previous studies suggest that the tremor activity originates in the cerebello-thalamocortical pathways. Alprazolam is a short-acting benzodiazepine that attenuates tremors in ET. The mechanisms that mediate the therapeutic action of alprazolam are unknown; however, in healthy subjects, benzodiazepines increase cortical beta activity. In this study, we investigated the effect of alprazolam both on beta and tremor-related cortical activity and on alterations in tremor presentation in ET patients. Therefore, we characterised the dynamics of tremor and cortical activity in ET patients after alprazolam intake. | |
Internacional
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Si |
JCR del ISI
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Si |
Título de la revista
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Plos One |
ISSN
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1932-6203 |
Factor de impacto JCR
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3,534 |
Información de impacto
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Volumen
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DOI
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Número de revista
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Desde la página
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1 |
Hasta la página
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11 |
Mes
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SIN MES |
Ranking
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