Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
Sensitive detection of major food allergens in breast milk: first gateway for allergenic contact during breastfeeding
Año:2015
Áreas de investigación
  • Ciencias naturales y ciencias de la salud,
  • Biología molecular, celular y genética,
  • Biología vegetal, animal y ecología,
  • Ciencias biológicas,
  • Ciencias ambientales
Datos
Descripción
Food allergy is recognized as a major public health issue, especially in early childhood. It has been hypothesized that early sensitization to food allergens maybe due to their ingestion as components dissolved in the milk during the breastfeeding, explaining reaction to a food, which has never been taken before. Thus, the aim of this work has been to detect the presence of the food allergens in breast milk by microarray technology. We produced a homemade microarray with antibodies produced against major food allergens. The antibody microarray was incubated with breast milk from 14 women collected from Fundación Jiménez Díaz Hospital. In this way, we demonstrated the presence of major foods allergens in breast milk. The analysis of allergens presented in breast milk could be a useful tool in allergy prevention and could provide us a key data on the role of this feeding in tolerance induction or sensitization in children.
Internacional
Si
JCR del ISI
Si
Título de la revista
Allergy
ISSN
0105-4538
Factor de impacto JCR
6,028
Información de impacto
Volumen
70
DOI
Número de revista
Desde la página
1024
Hasta la página
1027
Mes
SIN MES
Ranking
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: C Pastor-Vargas (Department of Immunology, IIS-Fundación Jimenez Diaz, Madrid, Spain.)
  • Autor: AS Maroto (Department of Immunology, IIS-Fundación Jimenez Diaz, Madrid, Spain.)
  • Autor: Araceli Diaz Perales (UPM)
  • Autor: M Villalba (Department of Biochemistry and Molecular Biology I, Universidad Complutense de Madrid, Madrid, Spain.)
  • Autor: N Casillas Díaz (Department of Pediatric, Fundación Jimenez Diaz, Madrid, Spain.)
  • Autor: F Vivanco (Department of Immunology, IIS-Fundación Jimenez Diaz, Madrid, Spain.)
  • Autor: J Cuesta-Herranz (Department of Allergy, Fundación Jimenez Diaz, Madrid, Spain.)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Biotecnología Vegetal
  • Centro o Instituto I+D+i: Centro de Biotecnología y Genómica de Plantas, CBGP
  • Departamento: Biotecnología - Biología Vegetal
S2i 2021 Observatorio de investigación @ UPM con la colaboración del Consejo Social UPM
Cofinanciación del MINECO en el marco del Programa INNCIDE 2011 (OTR-2011-0236)
Cofinanciación del MINECO en el marco del Programa INNPACTO (IPT-020000-2010-22)