Memorias de investigación
Artículos en revistas:
The N-end rule pathway regulates pathogen responses in plants
Año:2016
Áreas de investigación
  • Biología molecular, celular y genética
Datos
Descripción
To efficiently counteract pathogens, plants rely on a complex set of immune responses that are tightly regulated to allow the timely activation, appropriate duration and adequate amplitude of defense programs. The coordination of the plant immune response is known to require the activity of the ubiquitin/proteasome system, which controls the stability of proteins in eukaryotes. Here, we demonstrate that the N-end rule pathway, a subset of the ubiquitin/proteasome system, regulates the defense against a wide range of bacterial and fungal pathogens in the model plant Arabidopsis thaliana. We show that this pathway positively regulates the biosynthesis of plant-defense metabolites such as glucosinolates, as well as the biosynthesis and response to the phytohormone jasmonic acid, which plays a key role in plant immunity. Our results also suggest that the arginylation branch of the N-end rule pathway regulates the timing and amplitude of the defense program against the model pathogen Pseudomonas syringae AvrRpm1.
Internacional
Si
JCR del ISI
Si
Título de la revista
Sci Rep-Uk
ISSN
2045-2322
Factor de impacto JCR
5,578
Información de impacto
Datos JCR del año 2014
Volumen
6
DOI
10.1038/srep26020
Número de revista
Desde la página
26020
Hasta la página
.
Mes
MAYO
Ranking
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Participantes
  • Autor: Rémi de Marchi Maynooth University
  • Autor: Maud Sorel Maynooth University
  • Autor: Brian Mooney Maynooth University
  • Autor: Isabelle Fudal Université Paris Saclay
  • Autor: Kevin Goslin Maynooth University
  • Autor: Kamila Kwasniewska Trinity College Dublin
  • Autor: Patrick T. Ryan Trinity College Dublin
  • Autor: Marina Pfalz Université Paris Saclay
  • Autor: Juergen Kroymann Université Paris Saclay
  • Autor: Stephan Pollmann UPM
  • Autor: Angela Feechan University College Dublin
  • Autor: Frank Wellmer Trinity College Dublin
  • Autor: Susana Rivas Université de Toulouse
  • Autor: Emmanuelle Graciet Maynooth University
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Redes Reguladoras del Desarrollo y Respuesta a Estrés en Plantas