Observatorio de I+D+i UPM

Memorias de investigación
Artículos en revistas:
A fast pathway for fear in human amygdala
Año:2016
Áreas de investigación
  • Ciencias naturales y ciencias de la salud,
  • Medicina clínica y epidemiología,
  • Biomedicina
Datos
Descripción
A fast, subcortical pathway to the amygdala is thought to have evolved to enable rapid detection of threat. This pathway's existence is fundamental for understanding nonconscious emotional responses, but has been challenged as a result of a lack of evidence for short-latency fear-related responses in primate amygdala, including humans. We recorded human intracranial electrophysiological data and found fast amygdala responses, beginning 74-ms post-stimulus onset, to fearful, but not neutral or happy, facial expressions. These responses had considerably shorter latency than fear responses that we observed in visual cortex. Notably, fast amygdala responses were limited to low spatial frequency components of fearful faces, as predicted by magnocellular inputs to amygdala. Furthermore, fast amygdala responses were not evoked by photographs of arousing scenes, which is indicative of selective early reactivity to socially relevant visual information conveyed by fearful faces. These data therefore support the existence of a phylogenetically old subcortical pathway providing fast, but coarse, threat-related signals to human amygdala.
Internacional
Si
JCR del ISI
Si
Título de la revista
Nature Neuroscience
ISSN
1097-6256
Factor de impacto JCR
16,724
Información de impacto
Volumen
DOI
Número de revista
Desde la página
1041
Hasta la página
1049
Mes
SIN MES
Ranking
Esta actividad pertenece a memorias de investigación
Participantes
  • Autor: Constantino Mendez Bertolo (UPM)
  • Autor: Bryan Strange (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Grupo de Investigación: Tecnologías para Ciencias de la Salud
  • Departamento: Tecnología Fotónica y Bioingeniería
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