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Memorias de investigación
Artículos en revistas:
The transcription factor OBP4 controls root growth and promotes callus formation
Año:2016
Áreas de investigación
  • Biología molecular, celular y genética
Datos
Descripción
Plant growth and development require a continuous balance between cell division and differentiation. In root meristems, differentiated cells acquire specialized functions, losing their mitotic potential. Some plant cells, such as pericycle cells, have a remarkable plasticity to regenerate new organs. The molecular mechanisms underlying cell reprogramming are not completely known. In this work, a functional screening of transcription factors identified Arabidopsis OBP4 (OBF Binding Protein 4) as a novel regulator of root growth and cell elongation and differentiation. Overexpression of OBP4 regulates the levels of a large number of transcripts in roots, many involved in hormonal signaling and callus formation. OBP4 controls cell elongation and differentiation in root cells. OBP4 does not induce cell division in the root meristem, but promotes pericycle cell proliferation, forming callus-like structures at the root tip, as shown by the expression of stem cell markers. Callus formation is enhanced by ectopic expression of OBP4 in the wild-type or alf4-1, but is significantly reduced in roots that have lower levels of OBP4. Our data provide molecular insights into how differentiated root cells acquire the potential to generate callus, a pluripotent mass of cells that can regenerate fully functional plant organs
Internacional
Si
JCR del ISI
Si
Título de la revista
New Phytologist
ISSN
0028-646X
Factor de impacto JCR
7,21
Información de impacto
Datos JCR del año 2015
Volumen
DOI
10.1111/nph.14315
Número de revista
Desde la página
1
Hasta la página
15
Mes
SEPTIEMBRE
Ranking
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Participantes
  • Autor: Elena Ramirez Parra (UPM)
  • Autor: Juan Periañez Rodriguez (UPM)
  • Autor: Sara Navarro Neila (UPM)
  • Autor: Inmaculada Gude Rodriguez (UPM)
  • Autor: Miguel Angel Moreno Risueño (UPM)
  • Autor: Juan Carlos Del Pozo Benito (UPM)
Grupos de investigación, Departamentos, Centros e Institutos de I+D+i relacionados
  • Creador: Departamento: Biotecnología - Biología Vegetal
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