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Abstract
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| In this work we demonstrate, for the first 3me, the advantage of performing the biosensing process of a refrac3ve index op3cal biosensor under dry condi3ons, in comparison with the biosensing structure immersed in fluid. We developed a biosensing experiment over a specific transducer based on resonant nanopillars (R-NPs) arrays. The op3cal interroga3on to monitor the recogni3on events was firstly performed with the R-NPs in dry, only in contact with the air, and secondly with the R-NPs immersed in water. We observed a significant enhance in the sensi3vity of the biosensing curve response for the R-NPs in dry condi3ons, leading an improvement of the Limit of Detec3on (LoD) in more than one order of magnitude. According to this result, any interferometric op3cal bio-transducer for in-situ diagnosis will improve the sensi3vity in case it can operate in dry condi3ons. | |
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Place
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Escuela Técnica Superior de Ingenieros Industriales |
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Publication type
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Poster Congreso |